RedCloud Bio (the “Company”), an innovative biotech company integrating structural pharmacology and computational approaches to advance small molecule drug development, announced the upcoming presentation of preclinical data of H002, a next-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) in non-small cell lung cancer (NSCLC). The data will be presented at the 2022 Annual Meeting of the American Association for Cancer
Research (AACR), April 8-13, 2022 in New Orleans. H002 was discovered by RedCloud’s technology platform.
H002: A wide spectrum, highly selective fourth-generation EGFR inhibitor overcoming resistance harbouring C797S mutation in NSCLC
Apr 7, 2022,REDCLOUD BIO TO PRESENT PRECLINICAL DATA OF NEXT-GENERATION EGFR TKI H002 AT ANNUAL MEETING OF AMERICAN ASSOCIATION OF CANCER RESEARCH
Pipeline
Aug. 29, 2022, SHANGHAI, CHINA
RedCloud Bio (the "Company"), an innovative biotech company integrating structural pharmacology and computational approaches to advance small molecule drug discovery and development, announced completion of the first patient dosing for its next-generation EGFR TKI H002 in its H002-101CN study. The study is a multicenter phase I/IIa clinical trial in China for advanced NSCLC. H002 is a next-generation EGFR TKI discovered and developed by RedCloud Bio for treatment of prior EGFR TKI-resistant NSCLC, including those with C797S mutation.
Aug. 29, 2022, NEXT-GENERATION EGFR TKI H002 FROM REDCLOUD BIO COMPLETES FIRST DOSE IN NON-SMALL CELL LUNG CANCER
Mar 2, 2022, Shanghai China
- Drug Candidate Is First From Company To Enter Phase I/IIa
Clinical Trial
- H002 Has Potential To Overcome Resistance Driven By
Various EGFR C797S-Containing Mutations in Non-Small
Cell Lung Cancer
RedCloud Bio (the “Company”), an innovative biotech company integrating structural pharmacology and computational approaches
to advance small molecule drug development, announced today that the US Food and Drug Administration (FDA) has accepted the Company’s Investigational New Drug (IND) application, clearing the path to proceed Phase I/IIa clinical investigation of H002, a broad spectrum, highly selective, fourth-generation compound.
Mar 2, 2022,REDCLOUD BIO ANNOUNCES FDA ACCEPTANCE OF IND APPLICATION FOR NEXT-GENERATION EGFR INHIBITOR H002 IN NON-SMALL CELL LUNG CANCER
Pipeline
Jun 17, 2021 Nanjing China
RedCloud Bio announced the completion of B round financing of RMB100 million, led by CO-WIN Ventures and followed by KAITAI Capital. Existing shareholders, Sherpa Capital, Dayou Capital and Dynamic Balance Investment participated.
This round of financing will boost RedCloud Bio's development of small molecule drug research platform based on structural pharmacology, molecular dynamics-based structure optimization and accelerate the Company's IND process for its next generation RGFR inhibitor
Jun 17, 2021 - RedCloud Bio Announced the Completion of B Round Financing of RMB100 Million, Led by CO-WIN Ventures and Followed by KAITAI Capital
Corporate News
Nov 30, 2019 Nanjing China
Dayou Capital and Sherpa Capital Invested in A Round Financing for RedCloud Bio
- Support RedCloud Bio to establish a robust small molecule drug discovery program centered around structural pharmacology approach
- Fund the Company's research centers in Beijing and Shanghai
Dayou Capital and Sherpa Capital
Invested in A Round Financing for RedCloud Bio
Corporate News
May 23, 2019 - Beijing China.
Top oncology journal - Cancer Discovery(IF=24.37)published the latest results by Michael Eck, Nathanael Gray and Pasi Janne from Dana-Farber/Harvard Cancer Center,for their work on allosteric inhibitor JBJ-04-125-02 based on the design of the first fourth generation EGFR inhibitor EAI045, became a hot topic in the industry.
As one of the co-developers for world's first fourth generation EGFR inhibitor EAI045, as well as a core team member in Michael Eck's group, Prof. Caihong Yun revealed the status of next generation EGFR inhibitor to Chinese media for the first time.
The Next-Generation EGFR Inhibitor -What’s new about it? — The Latest Development of the 4th-Generation EGFR Inhibitor from the Perspective of Structural Pharmacology by Prof. Caihong Yun
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